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The Southern Ag Crossbow is a premium, low-volatile herbicide that delivers a one-two punch of 2,4-D and triclopyr—the exact combination serious land managers trust for woody brush and vines. This emulsion-based concentrate must be agitated constantly during use, but the payoff is a rapid foliar uptake that kills poison ivy, Virginia creeper, and winter creeper to the root without requiring multiple applications. The 32-ounce bottle mixes with 3 gallons of water plus a surfactant for full-coverage spraying over dense patches.

Users consistently report visible wilting within days on mature vines that had resisted other products. The low-volatile formula reduces off-target drift, making it safer to use near desirable plantings when applied carefully in calm conditions. One reviewer specifically called it the best product they’ve found for violets, oxalis, and poison ivy after years of trial and error with weaker brands.

This is not a product for casual spot-treating of lawn weeds—it’s a heavy-duty brush killer designed for established infestations. If your poison ivy has taken over a fence line, tree line, or overgrown area, Crossbow is the most effective solution in this roundup. The need for constant agitation and a dedicated sprayer is a minor trade-off for the elimination of woody vines in a single season.

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The Roundup Weed & Grass Killer₄ Concentrate is an updated formulation that combines triclopyr, diquat dibromide, and fluazifop-P-butyl for a triple-action assault that targets poison ivy, crabgrass, and broadleaf weeds. This gallon jug treats large areas—mix each gallon of spray solution over 300 square feet—making it a practical choice for clearing fence lines, garden plots, and walkways where poison ivy has spread. It becomes rainproof in as little as 30 minutes, which is a major advantage during unpredictable weather.

Users note visible results within hours, with full dieback in days. The formula kills weeds to the root, and reviewers confirm it eliminates established poison ivy and tough perennials. One long-time user emphasized that the product works exactly as advertised and is the most economical way to buy Roundup in bulk. The concentrate must be mixed with water and applied via a tank or hose-end sprayer, giving you control over the application rate.

Because this product is non-selective and potent, overspray will damage or kill any grass or ornamental plant it touches. Use a dedicated sprayer and apply only on calm days to avoid drift. The 1-gallon size provides substantial value for property owners managing large infestations, but beginners should start with a smaller bottle to test their application technique first.

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The Agrisel GlyPhoSel Pro packs 41% glyphosate in a water-based, low-odor formula that users consistently describe as far more potent than consumer-grade weed killers from big-box stores. The concentrate mixes at a low usage rate—just 4 ounces per gallon of water—and still annihilates tough vegetation including poison ivy, creeping charlie, and crabgrass. The manufacturer states it is pet safe once the spray has dried, which is a key consideration for homeowners with dogs or cats.

Reviewers praise its rapid results and the value per treatment. One verified buyer called it “much, much, much more powerful than what you’d buy at a big box store,” and another said it kills everything on contact. The flip side is that this extreme potency means overspray is exceptionally dangerous to nearby plants and grass. Several users warned that it will kill an entire lawn if applied carelessly, so it is best reserved for spot treatments in beds, along fences, or in areas where vegetation will be replaced.

This product is ideal for the gardener who wants professional-grade glyphosate without the high price tag of specialty brands. The lack of included components means you must supply your own sprayer, and the 32-ounce bottle covers up to 3,456 square feet at the recommended mix rate. For poison ivy patches, use the higher end of the mixing range to ensure the waxy leaves are fully saturated.

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The Fertilome Brush Killer Stump Killer is a triclopyr-based concentrate specifically designed for two distinct applications: foliar spraying of woody brush and direct application to freshly cut stumps. For poison ivy vines that have already been cut down, this product shines—apply it undiluted to the cut stump within 45 minutes of cutting, and it translocates into the root system to prevent regrowth. As a foliar spray, mix 8 ounces per gallon of water and coat the leaves thoroughly for effective control of established woody plants.

Users report excellent results on buckthorn, invasive trumpet vines, and small volunteer trees up to 3 inches in diameter. One reviewer noted that this product eliminated trumpet vines that had resisted other treatments for years. The cap has been cited as a leak issue by a few buyers, which is a valid concern given the concentrated herbicide inside—transfer the liquid to a sealed container or treat the cap with plumber’s tape as a precaution.

This is a specialized product that complements a foliar spray program. If you have already cut down large poison ivy vines or trees and need to stop regrowth, the Fertilome stump treatment is the most effective option here. For active green vines still attached to trees, use the foliar spray method. The 32-ounce bottle covers many stumps or a sizable brush area, making it a smart investment for ongoing property maintenance.

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The Bonide Chickweed, Clover & Oxalis Killer is a ready-to-use spray containing dicamba and triclopyr that targets broadleaf weeds while leaving lawns unharmed. This 128-ounce bottle treats up to 10,000 square feet, making it a practical choice for homeowners who want to control poison ivy growing in or near turfgrass without killing the lawn. It is nearly odorless and clear, and users report visible results by the next day on many weed types, including dandelions and chickweed.

It is important to note that this product targets broadleaf weeds specifically—it is not effective on crabgrass or other grassy weeds. One reviewer expressed disappointment with its performance on clover, while another praised its ability to wipe out entire patches of chickweed with a single spray. The built-in hand sprayer is adequate for small areas but users with large lawns recommend transferring the liquid to a pump sprayer for better coverage and control.

For poison ivy, this product is best used as a follow-up or for scattered plants growing among grass where non-selective herbicides would cause bare spots. The inclusion of triclopyr gives it some capability against woody vines, but established poison ivy may require the concentrate version for complete eradication. Avoid rain for at least 2 days after application to ensure the formula absorbs into the leaf structure.

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The Hi-Yield Killzall Super Concentrate offers a double-surfactant formulation that accelerates drying on plant leaves, allowing the glyphosate active ingredient to start working faster. At 32 ounces, this bottle treats up to 6,400 square feet when mixed at the standard rate, making it one of the most cost-effective non-selective killers in this roundup. The concentrated formula lets you dial in the strength—use a higher ratio for woody poison ivy vines and a standard mix for annual weeds.

Users consistently emphasize that this product kills everything it contacts, including grass, flowers, and shrubs. One reviewer stated, “If you are using any other weed killer, you are wasting your money.” Another noted that some weeds die in 1–3 days while tougher vines may stay green for 2 weeks before fully collapsing. This delayed action is normal for glyphosate on woody plants—the chemical must translocate to the roots before the top growth dies back.

The double-surfactant system is a genuine advantage for poison ivy because the waxy leaf cuticle is the primary barrier to herbicide uptake. The improved wetting and spreading ensures the spray covers the entire leaf surface rather than beading up and rolling off. As with all non-selective herbicides, wear full protective gear including a mask and gloves, and avoid application during windy conditions to protect nearby vegetation.

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The Control Solutions Eraser & Grass Killer Concentrate is a straightforward, budget-friendly option that delivers 41% glyphosate in a low-odor, water-based formula. A single quart (32 ounces) concentrates down to multiple gallons of spray solution—mix 8 ounces per gallon for general weed control or adjust the ratio for tougher woody vines. Users report that it is slower-acting than premium brands, typically showing results in 3–7 days depending on weather, but it eventually kills poison ivy, vines, and shrubs to the root.

One loyal buyer has used this product for 17 years and calls it a “killer for sure.” Others note that it is a better value than the consumer Roundup found at big-box stores, with the same active ingredient at a lower per-ounce cost. The formula has no residual soil activity, meaning you can replant treated areas once the product has dried and the weeds have died without worrying about ground contamination.

The main trade-off is speed and concentration—this is a glyphosate-only product without the added triclopyr that accelerates woody brush control. For thick, established poison ivy, you may need a second application 2–3 weeks after the first. Adding a surfactant improves results on waxy leaves. This is the right choice for the budget-conscious gardener who is willing to wait a little longer and possibly reapply for complete eradication of persistent vines.